OK, I was on my own - but I really loved living near Reading. Transport into London was excellent (although I wasn't working in London). London is like any big city like NYC or Paris - sure, there is a certain something to living directly in the city, but there's plenty of great times and other sorts of experience if you live out a ways and enjoy what the "suburbs" have to offer.

You may want to contact one of the FAWCO clubs in the London area (FAWCO - Member Clubs). These are American Women's Clubs for expats. They have a wealth of information about living in the area.
Cheers,
Bev