Probably not a bad idea to contact the Spanish consulate in Prague, no matter what. Technically, most consulates want you to apply through the consulate for the place where you are currently resident (in your case, Prague). But with non-EU citizens applying through consulates in the EU things sometimes get confused. (Sometimes it's just that the local consulate staff isn't familiar with the rules regarding Americans, or other non-EU citizens, so they try to send you back to the US for your paperwork.) Be firm, but polite and you'll manage.

I would imagine, too, that your media outlet may have some experience with this sort of thing and may already know the drill. Worth a quick question to them, in any event.
Cheers,
Bev