Here are a couple of photos of the Guggenheim museum in Bilbao, which I've seen on countless occasions (from the outside usually) as all my in laws live in Bilbao. The first shows the best view from the the other side of the river.
http://upload.wikimedia.org/wikipedi...eum_Bilbao.jpg
However people usually see this view as this is where the entrance is.
Archivo:The Guggenheim Bilbao in Spain 02-2005 001.jpg - Wikipedia, la enciclopedia libre
As you can see it's well worth while crossing the river, possibly by the Calatrava bridge, to get the other view.